Phenotypes associated with this allele

• Allele Symbol: Cant1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5612825
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cant1^tm1b(EUCOMM)Hmgu/Cant1^tm1b(EUCOMM)Hmgu	C57BL/6N-Cant1^tm1b(EUCOMM)Hmgu/Ieg	MGI:5756822
ht2	Cant1^tm1b(EUCOMM)Hmgu/Cant1^+	C57BL/6N-Cant1^tm1b(EUCOMM)Hmgu/Ieg	MGI:5756821

Genotype
MGI:5756822

hm1

• Allelic Composition: Cant1^{tm1b(EUCOMM)Hmgu}/Cant1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cant1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0624_1_E03

Data Sources

IMPC Data for Cant1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:211773 )

IMPC - HMGU

abnormal tail length ( J:211773 )

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5756821

ht2

• Allelic Composition: Cant1^{tm1b(EUCOMM)Hmgu}/Cant1⁺
• Genetic Background: C57BL/6N-Cant1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0624_1_E03

Data Sources

IMPC Data for Cant1

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

increased circulating amylase level ( J:211773 )

♂

IMPC - HMGU

increased circulating lipase level ( J:211773 )

♂

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

decreased total retina thickness ( J:211773 )

♂

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - HMGU