Analysis Tools
endocrine/exocrine glands
| N |
• in the absence of tamoxifen no thymus abnormalities are detected
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• treatment with tamoxifen at 12 and 24 months of age reverses thymus involution as measured by increase in thymus size and thymocyte numbers, and the presence of clearly defined cortical and medullary regions
• increase in the proliferation of thymic epithelial cells in mice treated at 12 and 24 months of age with tamoxifen compared to age matched controls
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immune system
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• treatment with tamoxifen at 12 and 24 months of age reverses thymus involution as measured by increase in thymus size and thymocyte numbers, and the presence of clearly defined cortical and medullary regions
• increase in the proliferation of thymic epithelial cells in mice treated at 12 and 24 months of age with tamoxifen compared to age matched controls
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• increase in the number of naive T cells in the peripheral immune system in mice treated at 12 and 24 months of age with tamoxifen compared to age matched controls
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hematopoietic system
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• treatment with tamoxifen at 12 and 24 months of age reverses thymus involution as measured by increase in thymus size and thymocyte numbers, and the presence of clearly defined cortical and medullary regions
• increase in the proliferation of thymic epithelial cells in mice treated at 12 and 24 months of age with tamoxifen compared to age matched controls
|
|
• increase in the number of naive T cells in the peripheral immune system in mice treated at 12 and 24 months of age with tamoxifen compared to age matched controls
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