muscle
• in mice fed a high fat diet
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vision/eye
homeostasis/metabolism
N |
• in the presence of excess insulin, mice exhibit normal blood glucose clearance rate
|
• mice fed a high fat diet exhibit almost constant weight after 4 weeks unlike wild-type mice that continue to gain weight
|
• under both light/dark and dark/dark conditions
|
• 2 times the liver insulin levels observed in wild-type mice
|
• after glucose or glibenclamide administration
• however, liver insulin content is increased
|
• during a glucose tolerance test
|
• reduced triglyceride to cholesterol molar ratio
• increased LDL cholesterol to HDL cholesterol ratio
|
• in mice are fed standard chow
|
• in mice are fed a high fat diet
|
• in mice are fed a high fat diet
|
• in mice are fed standard chow or a high fat diet
|
• in mice are fed standard chow or a high fat diet
|
• when mice are fed a high fat diet
|
• in mice are fed standard chow
|
• in mice fed standard chow and more so in mice fed a high fat diet
• increased circulating LDL and HDL triglyceride in mice fed a standard diet or a high fat diet
|
• in mice fed a high fat diet
|
• in mice fed a high fat diet
|
• meibomian gland circadian 3beta-hydroxyl-steroid dehydrogenase enzymatic activity is constantly low, with no significant elevation at zeitgeber time 03 compared to wild-type mice which show peaks at zeitgeber time 03
• mice show age-related decline in coenzyme NAD+ levels in the meibomian gland
|
growth/size/body
• when mice are fed standard chow
|
• mice fed a high fat diet exhibit almost constant weight after 4 weeks unlike wild-type mice that continue to gain weight
|
adipose tissue
• after 5 weeks on a high fat diet
|
• in mice are fed a high fat diet
|
behavior/neurological
N |
• mice exhibit normal food intake whether fed standard chow or a high fat diet
|
• loss of circadian rhythm in locomotor activity
|
liver/biliary system
• in mice fed a high fat diet
|
• in mice fed a high fat diet
|
endocrine/exocrine glands
• increased area at 44 weeks
• however, area is normal at 12 weeks
|
• after glucose or glibenclamide administration
• however, liver insulin content is increased
|
• excess sebum in mice fed a high fat diet
|
integument
• excess sebum in mice fed a high fat diet
|