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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Runx2-rtTA*M2)#Flng
transgene insertion, Fanxin Long
MGI:5613580
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm4(Wnt7b)Flng/Gt(ROSA)26Sor+
Tg(Runx2-rtTA*M2)#Flng/0
Tg(tetO-cre)1Jaw/0
involves: 129 * C57BL/6 MGI:5613585


Genotype
MGI:5613585
cn1
Allelic
Composition
Gt(ROSA)26Sortm4(Wnt7b)Flng/Gt(ROSA)26Sor+
Tg(Runx2-rtTA*M2)#Flng/0
Tg(tetO-cre)1Jaw/0
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm4(Wnt7b)Flng mutation (0 available); any Gt(ROSA)26Sor mutation (992 available)
Tg(Runx2-rtTA*M2)#Flng mutation (0 available)
Tg(tetO-cre)1Jaw mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• after doxycycline treatment
• in the long bones after doxycycline treatment
• proximal tibial trabecular bone volume/total volume is increased 6.6 fold at 2 months of age after doxycycline treatment
• markedly increased after doxycycline treatment
• marked increase in the trabecular bone mass in both primary and secondary ossification centers
• increased bone formation after doxycycline treatment

immune system
• after doxycycline treatment

hematopoietic system
• after doxycycline treatment





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory