Phenotypes associated with this allele

• Allele Symbol: Hnf4a^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5613635
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Hnf4a^tm1b(EUCOMM)Hmgu/Hnf4a^+	C57BL/6N-Hnf4a^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262634

Genotype
MGI:6262634

ht1

• Allelic Composition: Hnf4a^{tm1b(EUCOMM)Hmgu}/Hnf4a⁺
• Genetic Background: C57BL/6N-Hnf4a^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0635_7_A08

Data Sources

IMPC Data for Hnf4a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

endocrine/exocrine glands

enlarged thyroid gland ( J:211773 )

IMPC - HMGU

growth/size/body

decreased body weight ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

♂

IMPC - HMGU

increased circulating bilirubin level ( J:211773 )

♀

IMPC - HMGU

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HMGU

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HMGU

increased circulating calcium level ( J:211773 )

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - HMGU

cataract ( J:211773 )

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

♀

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

increased total retina thickness ( J:211773 )

IMPC - HMGU