Phenotypes associated with this allele

• Allele Symbol: Bltp1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5613665
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bltp1^tm1b(EUCOMM)Hmgu/Bltp1^tm1b(EUCOMM)Hmgu	B6N(Cg)-Bltp1^tm1b(EUCOMM)Hmgu/J	MGI:5767547
hm2	Bltp1^tm1b(EUCOMM)Hmgu/Bltp1^tm1b(EUCOMM)Hmgu	C57BL/6N-Bltp1^tm1b(EUCOMM)Hmgu/Ieg	MGI:5767546
ht3	Bltp1^tm1b(EUCOMM)Hmgu/Bltp1^+	B6N(Cg)-Bltp1^tm1b(EUCOMM)Hmgu/J	MGI:5797323
ht4	Bltp1^tm1b(EUCOMM)Hmgu/Bltp1^+	C57BL/6N-Bltp1^tm1b(EUCOMM)Hmgu/Ieg	MGI:5797322

Genotype
MGI:5767547

hm1

• Allelic Composition: Bltp1^{tm1b(EUCOMM)Hmgu}/Bltp1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: B6N(Cg)-Bltp1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0678_2_F05

Data Sources

IMPC Data for Bltp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - JAX

abnormal embryo size ( J:211773 )

♀

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - JAX

abnormal embryo size ( J:211773 )

♀

IMPC - JAX

integument

pallor ( J:211773 )

♀

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5767546

hm2

• Allelic Composition: Bltp1^{tm1b(EUCOMM)Hmgu}/Bltp1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Bltp1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0678_2_H07

Data Sources

IMPC Data for Bltp1

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5797323

ht3

• Allelic Composition: Bltp1^{tm1b(EUCOMM)Hmgu}/Bltp1⁺
• Genetic Background: B6N(Cg)-Bltp1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0678_2_F05

Data Sources

IMPC Data for Bltp1

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - JAX

increased thigmotaxis ( J:211773 )

♂

IMPC - JAX

decreased locomotor activity ( J:211773 )

♂

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

IMPC - JAX

Genotype
MGI:5797322

ht4

• Allelic Composition: Bltp1^{tm1b(EUCOMM)Hmgu}/Bltp1⁺
• Genetic Background: C57BL/6N-Bltp1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0678_2_H07

Data Sources

IMPC Data for Bltp1

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating glucose level ( J:211773 )

IMPC - HMGU

impaired glucose tolerance ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - HMGU

cataract ( J:211773 )

♀

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

♀

IMPC - HMGU