Phenotypes associated with this allele

• Allele Symbol: Hoxa2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5613670
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hoxa2^tm1b(EUCOMM)Wtsi/Hoxa2^tm1b(EUCOMM)Wtsi	C57BL/6N-Hoxa2^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262642
ht2	Hoxa2^tm1b(EUCOMM)Wtsi/Hoxa2^+	C57BL/6N-Hoxa2^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262641

Genotype
MGI:6262642

hm1

• Allelic Composition: Hoxa2^{tm1b(EUCOMM)Wtsi}/Hoxa2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Hoxa2^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0560_3_F04

Data Sources

IMPC Data for Hoxa2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262641

ht2

• Allelic Composition: Hoxa2^{tm1b(EUCOMM)Wtsi}/Hoxa2⁺
• Genetic Background: C57BL/6N-Hoxa2^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0560_3_F04

Data Sources

IMPC Data for Hoxa2

behavior/neurological

abnormal gait ( J:211773 )

♂

IMPC - HMGU

craniofacial

abnormal snout morphology ( J:211773 )

IMPC - HMGU

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

IMPC - HMGU

decreased respiratory quotient ( J:211773 )

♀

IMPC - HMGU

improved glucose tolerance ( J:211773 )

IMPC - HMGU

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - HMGU