Phenotypes associated with this allele

• Allele Symbol: Pde4dip^tm1Mhda
• Allele Name: targeted mutation 1, Martin Hrabe de Angelis
• Allele ID: MGI:5613970
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pde4dip^tm1Mhda/Pde4dip^tm1Mhda	B6.Cg-Pde4dip^tm1Mhda	MGI:5613971

Genotype
MGI:5613971

hm1

• Allelic Composition: Pde4dip^tm1Mhda/Pde4dip^tm1Mhda
• Genetic Background: B6.Cg-Pde4dip^tm1Mhda

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:216968 )

• in-utero or perinatal lethality

• homozygous mice are produced in only 68% of expected numbers

growth/size/body

growth/size/body region phenotype ( J:216968 )

N • no obvious structural abnormalities

nervous system

nervous system phenotype ( J:216968 )

N • brain size and cortical thickness are normal

behavior/neurological

behavior/neurological phenotype ( J:216968 )

N • normal association memory

N • normal ability of water deprived mice to distinguish between two odors using water as a reward

hyperactivity ( J:216968 )

• both sexes are more active and rear more in their home cages than do controls

• particularly in dark cycle

increased vertical activity ( J:216968 )

• increased rearing