All Phenotypes Rad50<tm4Jpt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rad50^tm4Jpt
targeted mutation 4, John H J Petrini
MGI:5614068

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Rad50^tm4Jpt/Rad50⁺	involves: 129/Sv * C57BL/6	MGI:5614081

Allelic Composition	Rad50^tm4Jpt/Rad50⁺
Genetic Background	involves: 129/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad50^tm4Jpt mutation (0 available); any Rad50 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

hydrocephaly ( J:209141 )

• in 4% of mice

neoplasm

increased liver tumor incidence ( J:209141 )

• multiple liver neoplasms are seen in 26% of mice

• most affected mice present hyperplastic nodules and/or adenomas

increased liver adenoma incidence ( J:209141 )

liver/biliary system

increased liver tumor incidence ( J:209141 )

• multiple liver neoplasms are seen in 26% of mice

• most affected mice present hyperplastic nodules and/or adenomas

increased liver adenoma incidence ( J:209141 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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