All Phenotypes Tg(Ins2-GP)1Kbuw MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Ins2-GP)1Kbuw
transgene insertion 1, Karin E Bornfeldt
MGI:5614121

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Atf6^tm1Hota/Atf6^tm1Hota Tg(Ins2-cre)25Mgn/0 Tg(Ins2-GP)1Kbuw/0	involves: C57BL/6 * DBA	MGI:5614220

Allelic Composition	Atf6^tm1Hota/Atf6^tm1Hota Tg(Ins2-cre)25Mgn/0 Tg(Ins2-GP)1Kbuw/0
Genetic Background	involves: C57BL/6 * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf6^tm1Hota mutation (1 available); any Atf6 mutation (45 available)
Tg(Ins2-cre)25Mgn mutation (2 available)
Tg(Ins2-GP)1Kbuw mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased physiological sensitivity to xenobiotic ( J:213542 )

• TUDCA-treated mice fail to exhibit a protective effect from diabetes with decreased insulin content and number of apoptotic cells in islets compared wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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