Phenotypes associated with this allele

• Allele Symbol: Ipo8^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5614578
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ipo8^tm1.1(KOMP)Vlcg/Ipo8^tm1.1(KOMP)Vlcg	C57BL/6N-Ipo8^tm1.1(KOMP)Vlcg/J	MGI:6262708
ht2	Ipo8^tm1.1(KOMP)Vlcg/Ipo8^+	C57BL/6N-Ipo8^tm1.1(KOMP)Vlcg/J	MGI:6678911

Genotype
MGI:6262708

hm1

• Allelic Composition: Ipo8^{tm1.1(KOMP)Vlcg}/Ipo8^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Ipo8^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 14312A-C12

Data Sources

IMPC Data for Ipo8

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - JAX

decreased grip strength ( J:211773 )

IMPC - JAX

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - JAX

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - JAX

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - JAX

abnormal optic disk morphology ( J:211773 )

IMPC - JAX

cataract ( J:211773 )

IMPC - JAX

Genotype
MGI:6678911

ht2

• Allelic Composition: Ipo8^{tm1.1(KOMP)Vlcg}/Ipo8⁺
• Genetic Background: C57BL/6N-Ipo8^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 14312A-C12

Data Sources

IMPC Data for Ipo8

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - JAX