Phenotypes associated with this allele

• Allele Symbol: Rbpj^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5614604
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rbpj^tm1b(EUCOMM)Hmgu/Rbpj^tm1b(EUCOMM)Hmgu	C57BL/6N-Rbpj^tm1b(EUCOMM)Hmgu/J	MGI:5767785
ht2	Rbpj^tm1b(EUCOMM)Hmgu/Rbpj^+	C57BL/6N-Rbpj^tm1b(EUCOMM)Hmgu/J	MGI:6263345

Genotype
MGI:5767785

hm1

• Allelic Composition: Rbpj^{tm1b(EUCOMM)Hmgu}/Rbpj^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Rbpj^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0733_5_F03

Data Sources

IMPC Data for Rbpj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263345

ht2

• Allelic Composition: Rbpj^{tm1b(EUCOMM)Hmgu}/Rbpj⁺
• Genetic Background: C57BL/6N-Rbpj^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0733_5_F03

Data Sources

IMPC Data for Rbpj

behavior/neurological

increased grip strength ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - JAX

improved glucose tolerance ( J:211773 )

♀

IMPC - JAX

skeleton

decreased bone mineral density ( J:211773 )

♀

IMPC - JAX