Phenotypes associated with this allele

• Allele Symbol: Slc5a5^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5614611
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc5a5^tm1b(KOMP)Wtsi/Slc5a5^tm1b(KOMP)Wtsi	C57BL/6N-Slc5a5^tm1b(KOMP)Wtsi/J	MGI:6263512

Genotype
MGI:6263512

hm1

• Allelic Composition: Slc5a5^{tm1b(KOMP)Wtsi}/Slc5a5^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Slc5a5^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0860_2_D04

Data Sources

IMPC Data for Slc5a5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - JAX

increased exploration in new environment ( J:211773 )

IMPC - JAX

tremors ( J:211773 )

♀

IMPC - JAX

increased grip strength ( J:211773 )

♀

IMPC - JAX

abnormal gait ( J:211773 )

♀

IMPC - JAX

hyperactivity ( J:211773 )

IMPC - JAX

abnormal sleep behavior ( J:211773 )

♀

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased urine creatinine level ( J:211773 )

♀

IMPC - JAX

increased circulating cholesterol level ( J:211773 )

IMPC - JAX

increased circulating HDL cholesterol level ( J:211773 )

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - JAX

integument

abnormal coat appearance ( J:211773 )

♀

IMPC - JAX

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - JAX

renal/urinary system

decreased urine creatinine level ( J:211773 )

♀

IMPC - JAX

skeleton

decreased bone mineral density ( J:211773 )

♀

IMPC - JAX

vision/eye

cornea deposits ( J:211773 )

♀

IMPC - JAX