Phenotypes associated with this allele

• Allele Symbol: Dnajb11^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5614700
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnajb11^tm1b(EUCOMM)Wtsi/Dnajb11^tm1b(EUCOMM)Wtsi	C57BL/6N-Dnajb11^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262295
ht2	Dnajb11^tm1b(EUCOMM)Wtsi/Dnajb11^+	C57BL/6N-Dnajb11^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262294

Genotype
MGI:6262295

hm1

• Allelic Composition: Dnajb11^{tm1b(EUCOMM)Wtsi}/Dnajb11^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dnajb11^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0821_2_F10

Data Sources

IMPC Data for Dnajb11

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262294

ht2

• Allelic Composition: Dnajb11^{tm1b(EUCOMM)Wtsi}/Dnajb11⁺
• Genetic Background: C57BL/6N-Dnajb11^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0821_2_F10

Data Sources

IMPC Data for Dnajb11

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - HMGU

cardiovascular system

dilated aorta ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

vision/eye

persistence of hyaloid vascular system ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU