Phenotypes associated with this allele

• Allele Symbol: Med25^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5615649
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Med25^tm1b(KOMP)Wtsi/Med25^tm1b(KOMP)Wtsi	C57BL/6N-Med25^tm1b(KOMP)Wtsi/Ics	MGI:5757353
ht2	Med25^tm1b(KOMP)Wtsi/Med25^+	C57BL/6N-Med25^tm1b(KOMP)Wtsi/Ics	MGI:5757352

Genotype
MGI:5757353

hm1

• Allelic Composition: Med25^{tm1b(KOMP)Wtsi}/Med25^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Med25^{tm1b(KOMP)Wtsi}/Ics
• Cell Lines: EPD0328_5_F06

Data Sources

IMPC Data for Med25

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757352

ht2

• Allelic Composition: Med25^{tm1b(KOMP)Wtsi}/Med25⁺
• Genetic Background: C57BL/6N-Med25^{tm1b(KOMP)Wtsi}/Ics
• Cell Lines: EPD0328_5_F06

Data Sources

IMPC Data for Med25

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - ICS

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - ICS

abnormal motor capabilities/coordination/movement ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - ICS

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - ICS

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - ICS

skeleton

short tibia ( J:211773 )

♀

IMPC - ICS

vision/eye

decreased total retina thickness ( J:211773 )

IMPC - ICS