Phenotypes associated with this allele

• Allele Symbol: Mapt^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5615650
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mapt^tm1b(EUCOMM)Hmgu/Mapt^tm1b(EUCOMM)Hmgu	C57BL/6N-Mapt^tm1b(EUCOMM)Hmgu/Ics	MGI:5757342

Genotype
MGI:5757342

hm1

• Allelic Composition: Mapt^{tm1b(EUCOMM)Hmgu}/Mapt^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Mapt^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0729_5_A02

Data Sources

IMPC Data for Mapt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - ICS

increased fluid intake ( J:211773 )

IMPC - ICS

decreased grip strength ( J:211773 )

♂

IMPC - ICS

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - ICS

growth/size/body

polycystic kidney ( J:211773 )

♀

IMPC - ICS

renal/urinary system

polycystic kidney ( J:211773 )

♀

IMPC - ICS

vision/eye

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - ICS

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - ICS

decreased total retina thickness ( J:211773 )

♂

IMPC - ICS