Phenotypes associated with this allele

• Allele Symbol: Dclre1c^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:5615709
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dclre1c^m1Btlr/Dclre1c^m1Btlr	C57BL/6J-Dclre1c^m1Btlr	MGI:5615969

Genotype
MGI:5615969

hm1

• Allelic Composition: Dclre1c^m1Btlr/Dclre1c^m1Btlr
• Genetic Background: C57BL/6J-Dclre1c^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased neutrophil cell number ( J:217790 )

decreased B cell number ( J:217790 )

increased NK cell number ( J:217790 )

decreased T cell number ( J:217790 )

decreased single-positive T cell number ( J:217790 )

increased macrophage cell number ( J:217790 )

decreased IgM level ( J:217790 )

• T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll) is diminished

impaired humoral immune response ( J:217790 )

• T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll) is diminished

decreased response to antigen ( J:217790 )

• T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll) is diminished

hematopoietic system

increased neutrophil cell number ( J:217790 )

decreased B cell number ( J:217790 )

increased NK cell number ( J:217790 )

decreased T cell number ( J:217790 )

decreased single-positive T cell number ( J:217790 )

increased macrophage cell number ( J:217790 )

decreased IgM level ( J:217790 )

• T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll) is diminished