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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rorcm2Btlr
mutation 1, Bruce Beutler
MGI:5615712
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rorcm2Btlr/Rorcm2Btlr C57BL/6J-Rorcm2Btlr MGI:5615994


Genotype
MGI:5615994
hm1
Allelic
Composition		 Rorcm2Btlr/Rorcm2Btlr
Genetic
Background		 C57BL/6J-Rorcm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rorcm2Btlr mutation (0 available); any Rorc mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgM level ( J:217792 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
impaired humoral immune response ( J:217792 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
decreased response to antigen ( J:217792 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system
decreased IgM level ( J:217792 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory