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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Irf7M2Btlr
mutation 2, Bruce Beutler
MGI:5615723
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Irf7M2Btlr/Irf7M2Btlr C57BL/6J-Irf7M2Btlr MGI:5615978
ht2
 		Irf7M2Btlr/Irf7+ C57BL/6J-Irf7M2Btlr MGI:5615979


Genotype
MGI:5615978
hm1
Allelic
Composition		 Irf7M2Btlr/Irf7M2Btlr
Genetic
Background		 C57BL/6J-Irf7M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf7M2Btlr mutation (0 available); any Irf7 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA

immune system
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA




Genotype
MGI:5615979
ht2
Allelic
Composition		 Irf7M2Btlr/Irf7+
Genetic
Background		 C57BL/6J-Irf7M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf7M2Btlr mutation (0 available); any Irf7 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA

immune system
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory