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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trp63tm2Aam
targeted mutation 2, Alea A Mills
MGI:5616188
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Trp63tm2Aam/Trp63tm2Aam Not Specified MGI:5616191


Genotype
MGI:5616191
cn1
Allelic
Composition		 Trp63tm2Aam/Trp63tm2Aam
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63tm2Aam mutation (0 available); any Trp63 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cellular replicative senescence ( J:158291 )
• Ras-expressing MEFs infected with Cre exhibit compromised oncogene-induced senescence




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory