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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa
targeted mutation 3, Dieter Saur
MGI:5616874
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Psmd11tm1.1Qit/Psmd11tm1.1Qit
Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa/Gt(ROSA)26Sor+
Tg(ACTFLPe)9205Dym/0 		involves: 129S6/SvEvTac * C57BL/6 * SJL MGI:7643474


Genotype
MGI:7643474
cn1
Allelic
Composition		 Psmd11tm1.1Qit/Psmd11tm1.1Qit
Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa/Gt(ROSA)26Sor+
Tg(ACTFLPe)9205Dym/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Psmd11tm1.1Qit mutation (0 available); any Psmd11 mutation (41 available)
Tg(ACTFLPe)9205Dym mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased apoptosis ( J:301736 )
• mouse embryonic fibroblasts (MEFs) from E14.5 embryos treated with 4-hydroxytamoxifen to induce deletion of the floxed Psmd11 allele exhibit increased apoptosis




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory