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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Drd1tm1.1Mmsh
targeted mutation 1.1, Masayoshi Mishina
MGI:5617500
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Drd1tm1.1Mmsh/Drd1tm1.1Mmsh
Gng7tm1(cre)Mmsh/?
involves: C57BL/6N MGI:5698151


Genotype
MGI:5698151
cn1
Allelic
Composition
Drd1tm1.1Mmsh/Drd1tm1.1Mmsh
Gng7tm1(cre)Mmsh/?
Genetic
Background
involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drd1tm1.1Mmsh mutation (1 available); any Drd1 mutation (70 available)
Gng7tm1(cre)Mmsh mutation (0 available); any Gng7 mutation (75 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal nociceptive response to electric shock
• smaller freezing response 1 day after foot shock conditioning than seen in controls
• very little freezing response 10 minutes after a single shock
• five consecutive shocks on the first day increases freezing response but response is still less than controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory