Phenotypes associated with this allele

• Allele Symbol: Eif1ad^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5617790
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eif1ad^tm1b(EUCOMM)Hmgu/Eif1ad^tm1b(EUCOMM)Hmgu	C57BL/6N-Eif1ad^tm1b(EUCOMM)Hmgu/Bay	MGI:6262353
ht2	Eif1ad^tm1b(EUCOMM)Hmgu/Eif1ad^+	C57BL/6N-Eif1ad^tm1b(EUCOMM)Hmgu/Bay	MGI:6492814

Genotype
MGI:6262353

hm1

• Allelic Composition: Eif1ad^{tm1b(EUCOMM)Hmgu}/Eif1ad^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Eif1ad^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0780_3_A03

Data Sources

IMPC Data for Eif1ad

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6492814

ht2

• Allelic Composition: Eif1ad^{tm1b(EUCOMM)Hmgu}/Eif1ad⁺
• Genetic Background: C57BL/6N-Eif1ad^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0780_3_A03

Data Sources

IMPC Data for Eif1ad

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - HAR

hematopoietic system

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR

immune system

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR