Phenotypes associated with this allele

• Allele Symbol: Adss2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5617796
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adss2^tm1b(EUCOMM)Wtsi/Adss2^tm1b(EUCOMM)Wtsi	C57BL/6N-Adss2^tm1b(EUCOMM)Wtsi/Bay	MGI:6261822
ht2	Adss2^tm1b(EUCOMM)Wtsi/Adss2^+	C57BL/6N-Adss2^tm1b(EUCOMM)Wtsi/Bay	MGI:6261821

Genotype
MGI:6261822

hm1

• Allelic Composition: Adss2^{tm1b(EUCOMM)Wtsi}/Adss2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Adss2^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0458_4_G04

Data Sources

IMPC Data for Adss2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6261821

ht2

• Allelic Composition: Adss2^{tm1b(EUCOMM)Wtsi}/Adss2⁺
• Genetic Background: C57BL/6N-Adss2^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0458_4_G04

Data Sources

IMPC Data for Adss2

hematopoietic system

decreased eosinophil cell number ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

♀

IMPC - HAR

decreased blood urea nitrogen level ( J:211773 )

♀

IMPC - HAR

increased circulating HDL cholesterol level ( J:211773 )

♀

IMPC - HAR

immune system

decreased eosinophil cell number ( J:211773 )

♀

IMPC - HAR