Phenotypes associated with this allele

• Allele Symbol: Gpr52^tm1Kohi
• Allele Name: targeted mutation 1, Hidetoshi Komatsu
• Allele ID: MGI:5618129
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gpr52^tm1Kohi/Gpr52^tm1Kohi	involves: 129S/SvEv	MGI:5618155

Genotype
MGI:5618155

hm1

• Allelic Composition: Gpr52^tm1Kohi/Gpr52^tm1Kohi
• Genetic Background: involves: 129S/SvEv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:214470 )

N • mice exhibit normal locomotor activity under normal conditions and after exposure to methamphetamine

enhanced behavioral response to xenobiotic ( J:214470 )

• mice treated with MK-801 exhibit increased sensitivity to startle response compared with control mice

decreased anxiety-related response ( J:214470 )

• in an open field test, mice stay and move around the central region longer than control mice

increased startle reflex ( J:214470 )

• in mice treated with MK-801

nervous system

nervous system phenotype ( J:214470 )

N • untreated and MK-801-treated mice exhibit normal prepulse inhibition

N • normal brain weight and morphology

growth/size/body

growth/size/body region phenotype ( J:214470 )

N • normal body weight