Phenotypes associated with this allele

• Allele Symbol: Creb1^tm1.1Khk
• Allele Name: targeted mutation 1.1, Klaus Kaestner
• Allele ID: MGI:5618173
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Creb1^tm1.1Khk/Creb1^tm1.1Khk	involves: C57BL/6J * FVB/N	MGI:5882223

Genotype
MGI:5882223

cn1

• Allelic Composition: Creb1^tm1.1Khk/Creb1^tm1.1Khk
• Genetic Background: involves: C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:210887 )

N • following injection of adeno-associated virus (AAV)-cre under the control of a hepatocyte-specific promoter (Serpina7), no difference is observed in fed and fasted glucose levels, or in glucose, insulin and glucagon tolerance in mice fed a normal chow or a high-fat diet relative to control mice

N • after an overnight fast, mRNA levels of key gluconeogenic genes remain unaffected in the liver of AAV-cre injected chow fed or high-fat diet fed mice relative to control mice