About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Clcn2tm2.1Tjj
targeted mutation 2.1, Thomas J Jentsch
MGI:5618265
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Clcn2tm2.1Tjj/Clcn2tm2.1Tjj involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5646506
cx2
 		Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Hepacamtm1.2Tjj/Hepacamtm1.2Tjj 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac MGI:5646507


Genotype
MGI:5646506
hm1
Allelic
Composition		 Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clcn2tm2.1Tjj mutation (0 available); any Clcn2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:210308 )
N
• no myelin vacuolization is seen at 17 weeks of age




Genotype
MGI:5646507
cx2
Allelic
Composition		 Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Hepacamtm1.2Tjj/Hepacamtm1.2Tjj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clcn2tm2.1Tjj mutation (0 available); any Clcn2 mutation (40 available)
Hepacamtm1.2Tjj mutation (0 available); any Hepacam mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelin sheath morphology ( J:210308 )
• myelin vacuolization is increased compared to either single homozygote




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory