Phenotypes associated with this allele

• Allele Symbol: Dvl3^b2b2866Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
• Allele ID: MGI:5618437
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dvl3^b2b2866Clo/Dvl3^b2b2866Clo	C57BL/6J-Dvl3^b2b2866Clo	MGI:5618440

Genotype
MGI:5618440

hm1

• Allelic Composition: Dvl3^b2b2866Clo/Dvl3^b2b2866Clo
• Genetic Background: C57BL/6J-Dvl3^b2b2866Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant (E14.5) presents with malaligned outflow tracts, later diagnosed as double outlet right ventricle (DORV) by ECM histopathology.

cardiovascular system

double outlet right ventricle, ventricular defect committed to aorta ( J:175213 )

craniofacial

micrognathia ( J:175213 )

short snout ( J:175213 )

skeleton

micrognathia ( J:175213 )

renal/urinary system

hydronephrosis ( J:175213 )

growth/size/body

short snout ( J:175213 )

vision/eye

enophthalmos ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )