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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		ElaneM1Btlr
mutation 1, Bruce Beutler
MGI:5619132
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		ElaneM1Btlr/ElaneM1Btlr C57BL/6J-ElaneM1Btlr MGI:5619280


Genotype
MGI:5619280
hm1
Allelic
Composition		 ElaneM1Btlr/ElaneM1Btlr
Genetic
Background		 C57BL/6J-ElaneM1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ElaneM1Btlr mutation (0 available); any Elane mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:218967 )
• some mice exhibit decreased TNF secretion in response to the Toll-like receptor 4 (TLR4) ligand LPS




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory