Phenotypes associated with this allele

• Allele Symbol: Pcgf1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5620906
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pcgf1^tm1.1(KOMP)Vlcg/Pcgf1^tm1.1(KOMP)Vlcg	C57BL/6N-Pcgf1^tm1.1(KOMP)Vlcg/J	MGI:5767753
ht2	Pcgf1^tm1.1(KOMP)Vlcg/Pcgf1^+	C57BL/6N-Pcgf1^tm1.1(KOMP)Vlcg/J	MGI:5888402

Genotype
MGI:5767753

hm1

• Allelic Composition: Pcgf1^{tm1.1(KOMP)Vlcg}/Pcgf1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Pcgf1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 18632A-A2

Data Sources

IMPC Data for Pcgf1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - JAX

abnormal heart looping ( J:211773 )

IMPC - JAX

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - JAX

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - JAX

abnormal embryo turning ( J:211773 )

IMPC - JAX

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal neural tube closure ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - JAX

abnormal forebrain development ( J:211773 )

IMPC - JAX

abnormal midbrain development ( J:211773 )

IMPC - JAX

Genotype
MGI:5888402

ht2

• Allelic Composition: Pcgf1^{tm1.1(KOMP)Vlcg}/Pcgf1⁺
• Genetic Background: C57BL/6N-Pcgf1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 18632A-A2

Data Sources

IMPC Data for Pcgf1

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - JAX

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - JAX