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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col1a1tm1(tetO-Stat1)Biat
targeted mutation 1, Biomodels Austria
MGI:5621001
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Col1a1tm1(tetO-Stat1)Biat/Col1a1tm1(tetO-Stat1)Biat
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Stat1tm1Dlv/Stat1tm1Dlv 		involves: 129S/SvEv * 129S4/SvJae * C57BL/6 MGI:5698051


Genotype
MGI:5698051
cx1
Allelic
Composition		 Col1a1tm1(tetO-Stat1)Biat/Col1a1tm1(tetO-Stat1)Biat
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Stat1tm1Dlv/Stat1tm1Dlv
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm1(tetO-Stat1)Biat mutation (1 available); any Col1a1 mutation (163 available)
Gt(ROSA)26Sortm1(rtTA*M2)Jae mutation (30 available); any Gt(ROSA)26Sor mutation (993 available)
Stat1tm1Dlv mutation (6 available); any Stat1 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal susceptibility to infection induced morbidity/mortality ( J:212694 )
• Vesicular Stomatitis Virus or Encephalomyocarditis Virus infection results in death
• mice treated with doxycycline prior to viral infection survive at rates only slightly lower than wild-type controls

immune system
abnormal susceptibility to infection induced morbidity/mortality ( J:212694 )
• Vesicular Stomatitis Virus or Encephalomyocarditis Virus infection results in death
• mice treated with doxycycline prior to viral infection survive at rates only slightly lower than wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory