hematopoietic system
N |
• no spontaneous development of abnormal phenotype
|
• marked drop in hematopoietic cell after tamoxifen administration
|
pale spleen
(
J:212681
)
mortality/aging
• die within several days of tamoxifen administration
|
liver/biliary system
• microembolic and necrotic areas in the liver after tamoxifen administration
(J:212681)
• with white spots after tamoxifen administration
(J:212681)
|
cellular
• massive apoptosis in major organs after tamoxifen administration
|
immune system
pale spleen
(
J:212681
)
• elevated levels of GM-CSF after tamoxifen administration
|
• particularly elevated after tamoxifen administration
|
• elevated after tamoxifen administration
|
• particularly elevated after tamoxifen administration
|
• particularly elevated TNF-alpha levels after tamoxifen administration
|
homeostasis/metabolism
• elevated levels of GM-CSF after tamoxifen administration
|
• particularly elevated after tamoxifen administration
|
• elevated after tamoxifen administration
|
• particularly elevated after tamoxifen administration
|
• particularly elevated TNF-alpha levels after tamoxifen administration
|
• die within several days of tamoxifen administration
|
endocrine/exocrine glands