Phenotypes associated with this allele

• Allele Symbol: Emc3^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5629314
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Emc3^tm1b(EUCOMM)Wtsi/Emc3^tm1b(EUCOMM)Wtsi	C57BL/6N-Emc3^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262367
ht2	Emc3^tm1b(EUCOMM)Wtsi/Emc3^+	C57BL/6N-Emc3^tm1b(EUCOMM)Wtsi/Ieg	MGI:6461241

Genotype
MGI:6262367

hm1

• Allelic Composition: Emc3^{tm1b(EUCOMM)Wtsi}/Emc3^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Emc3^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0541_2_C06

Data Sources

IMPC Data for Emc3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6461241

ht2

• Allelic Composition: Emc3^{tm1b(EUCOMM)Wtsi}/Emc3⁺
• Genetic Background: C57BL/6N-Emc3^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0541_2_C06

Data Sources

IMPC Data for Emc3

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - HMGU

behavior/neurological

decreased vertical activity ( J:211773 )

IMPC - HMGU

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - HMGU

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - HMGU