Analysis Tools
mortality/aging
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• no mice are recovered at weaning
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Allele Symbol Allele Name Allele ID |
Adamts9Mhdaund4 Martin Hrabe de Angelis undefined mutation 4 MGI:5629512 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• no mice are recovered at weaning
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• unpigmented ring of epidermis, but normal dermis pigmentation, in the middle of the tail with less than 100% penetrance and fewer animals exhibiting both dorsal and ventral hypopigmentation
• however, body pigmentation is otherwise normal
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• unpigmented ring of epidermis, but normal dermis pigmentation, in the middle of the tail with less than 100% penetrance and fewer animals exhibiting both dorsal and ventral hypopigmentation
• however, body pigmentation is otherwise normal
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• unpigmented ring of epidermis, but normal dermis pigmentation, in the middle of the tail with less than 100% penetrance and fewer animals exhibiting both dorsal and ventral hypopigmentation
• however, body pigmentation is otherwise normal
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• unpigmented ring of epidermis, but normal dermis pigmentation, in the middle of the tail with less than 100% penetrance and fewer animals exhibiting both dorsal and ventral hypopigmentation
• however, body pigmentation is otherwise normal
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• unpigmented ring of epidermis, but normal dermis pigmentation, in the middle of the tail with less than 100% penetrance and fewer animals exhibiting both dorsal and ventral hypopigmentation
• however, body pigmentation is otherwise normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at P8, over half of mice exhibit an area of reduced melanoblasts in the tail unlike in wild-type mice
• however, distribution of melanoblasts in the dermis is normal
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• at E18.5/P0, all mice exhibit an area of reduced melanoblasts in the tail compared with just over half of wild-type mice
• at P2, most mice exhibit an area of reduced melanoblasts in the tail compared with few wild-type mice
• at P8, over half of mice exhibit an area of reduced melanoblasts in the tail unlike in wild-type mice
• the boundaries of hypopigmentation are stable over time
• at P28, hypopigmented epidermis in the skin contains no lacZ-positive cells in the scales or hair with some scales at the edge being lightly pigmented and containing less dendritic melanocytes
• however, melanoblast distribution in the tail is normal at E16.5 and distribution of melanoblasts in the dermis is normal
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• at P8, over half of mice exhibit an area of reduced melanoblasts in the tail unlike in wild-type mice
• however, distribution of melanoblasts in the dermis is normal
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• at E18.5/P0, all mice exhibit an area of reduced melanoblasts in the tail compared with just over half of wild-type mice
• at P2, most mice exhibit an area of reduced melanoblasts in the tail compared with few wild-type mice
• at P8, over half of mice exhibit an area of reduced melanoblasts in the tail unlike in wild-type mice
• the boundaries of hypopigmentation are stable over time
• at P28, hypopigmented epidermis in the skin contains no lacZ-positive cells in the scales or hair with some scales at the edge being lightly pigmented and containing less dendritic melanocytes
• however, melanoblast distribution in the tail is normal at E16.5 and distribution of melanoblasts in the dermis is normal
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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