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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stk31tm2Jw
targeted mutation 2, Jeremy Wang
MGI:5629553
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Stk31tm2Jw/Stk31tm2Jw B6J.Cg-Stk31tm2Jw MGI:5660383
hm2
 		Stk31tm2Jw/Stk31tm2Jw involves: 129S4/SvJae * C57BL/6 * C57BL/6J MGI:5660381


Genotype
MGI:5660383
hm1
Allelic
Composition		 Stk31tm2Jw/Stk31tm2Jw
Genetic
Background		 B6J.Cg-Stk31tm2Jw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stk31tm2Jw mutation (0 available); any Stk31 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:213823 )
N
• after backcrossing to the C57BL/6J strain for ten generations, males are still fertile with normal testis weight and normal sperm count at 8 weeks of age




Genotype
MGI:5660381
hm2
Allelic
Composition		 Stk31tm2Jw/Stk31tm2Jw
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stk31tm2Jw mutation (0 available); any Stk31 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:213823 )
N
• both male and female mice appear to be grossly healthy and fertile
• males exhibit normal testis size and testis histology at 8 weeks of age
• following exposure of young female pups to gamma-irradiation, both wild-type and mutant ovaries lack primordial follicles, suggesting that the DNA damage checkpoint in oocytes is intact




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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory