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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nxf1em1Haml
endonuclease-mediated mutation 1, Bruce Hamilton
MGI:5629959
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Nxf1em1Haml/Nxf1Mvb1
Pitpnavb/Pitpnavb
involves: C57BL/6 * DBA/2J MGI:5629975
cx2
Nxf1em1Haml/Nxf1+
Pitpnavb/Pitpnavb
involves: C57BL/6J * DBA/2J MGI:5629974


Genotype
MGI:5629975
cx1
Allelic
Composition
Nxf1em1Haml/Nxf1Mvb1
Pitpnavb/Pitpnavb
Genetic
Background
involves: C57BL/6 * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxf1em1Haml mutation (1 available); any Nxf1 mutation (36 available)
Nxf1Mvb1 mutation (1 available); any Nxf1 mutation (36 available)
Pitpnavb mutation (1 available); any Pitpna mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• improved survival compared with Nxf1Mvb1-C57BL/6J/Nxf1Mvb1-CAST/Ei Pitpnavb/Pitpnavb mice

behavior/neurological
• reduced tremor score compared with Nxf1Mvb1-C57BL/6J/Nxf1Mvb1-CAST/Ei Pitpnavb/Pitpnavb mice




Genotype
MGI:5629974
cx2
Allelic
Composition
Nxf1em1Haml/Nxf1+
Pitpnavb/Pitpnavb
Genetic
Background
involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxf1em1Haml mutation (1 available); any Nxf1 mutation (36 available)
Pitpnavb mutation (1 available); any Pitpna mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• improved survival compared with Nxf1Mvb1-C57BL/6J Pitpnavb double homozygotes

behavior/neurological
• reduced tremor score compared with Nxf1Mvb1-C57BL/6J Pitpnavb double homozygotes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory