Phenotypes associated with this allele

• Allele Symbol: Plcb4^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5630063
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plcb4^tm1b(EUCOMM)Wtsi/Plcb4^tm1b(EUCOMM)Wtsi	C57BL/6N-Plcb4^tm1b(EUCOMM)Wtsi/Tcp	MGI:6263181

Genotype
MGI:6263181

hm1

• Allelic Composition: Plcb4^{tm1b(EUCOMM)Wtsi}/Plcb4^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Plcb4^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0590_4_C09

Data Sources

IMPC Data for Plcb4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - UCD

increased grip strength ( J:211773 )

IMPC - UCD

abnormal locomotor behavior ( J:211773 )

♂

IMPC - UCD

abnormal gait ( J:211773 )

IMPC - UCD

increased vertical activity ( J:211773 )

♀

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

increased lean body mass ( J:211773 )

♂

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

hydrometra ( J:211773 )

♀

IMPC - UCD

skeleton

increased bone mineral content ( J:211773 )

IMPC - UCD