hematopoietic system
• homozygous mutant mice exhibit an increased frequency of B1a B cells in the peripheral B1 B cell compartment.
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• mice homozygous for this mutation exhibit a decreased frequency of B cells in the periphery.
• homozygous mutant mice have a reduced frequency of peripheral IgM+ B cells.
• homozygous mutant mice have a decrease in the percentage of peripheral IgD+ B cells.
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immune system
• homozygous mutant mice exhibit an increased frequency of B1a B cells in the peripheral B1 B cell compartment.
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• mice homozygous for this mutation exhibit a decreased frequency of B cells in the periphery.
• homozygous mutant mice have a reduced frequency of peripheral IgM+ B cells.
• homozygous mutant mice have a decrease in the percentage of peripheral IgD+ B cells.
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