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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cd22m3Btlr
mtutaion 3, Bruce Beutler
MGI:5632158
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cd22m3Btlr/Cd22m3Btlr C57BL/6J-Cd22m3Btlr MGI:5632159


Genotype
MGI:5632159
hm1
Allelic
Composition
Cd22m3Btlr/Cd22m3Btlr
Genetic
Background
C57BL/6J-Cd22m3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd22m3Btlr mutation (0 available); any Cd22 mutation (64 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• homozygous mutant mice exhibit an increased frequency of B1a B cells in the peripheral B1 B cell compartment.
• mice homozygous for this mutation exhibit a decreased frequency of B cells in the periphery.
• homozygous mutant mice have a reduced frequency of peripheral IgM+ B cells.
• homozygous mutant mice have a decrease in the percentage of peripheral IgD+ B cells.

immune system
• homozygous mutant mice exhibit an increased frequency of B1a B cells in the peripheral B1 B cell compartment.
• mice homozygous for this mutation exhibit a decreased frequency of B cells in the periphery.
• homozygous mutant mice have a reduced frequency of peripheral IgM+ B cells.
• homozygous mutant mice have a decrease in the percentage of peripheral IgD+ B cells.





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory