Phenotypes associated with this allele

• Allele Symbol: Fbxo30^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5632527
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo30^tm1b(KOMP)Wtsi/Fbxo30^tm1b(KOMP)Wtsi	C57BL/6N-Fbxo30^tm1b(KOMP)Wtsi/J	MGI:6262426
ht2	Fbxo30^tm1b(KOMP)Wtsi/Fbxo30^+	C57BL/6N-Fbxo30^tm1b(KOMP)Wtsi/J	MGI:6461264

Genotype
MGI:6262426

hm1

• Allelic Composition: Fbxo30^{tm1b(KOMP)Wtsi}/Fbxo30^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Fbxo30^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0490_5_F02

Data Sources

IMPC Data for Fbxo30

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6461264

ht2

• Allelic Composition: Fbxo30^{tm1b(KOMP)Wtsi}/Fbxo30⁺
• Genetic Background: C57BL/6N-Fbxo30^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0490_5_F02

Data Sources

IMPC Data for Fbxo30

behavior/neurological

decreased startle reflex ( J:211773 )

♂

IMPC - JAX

hyperactivity ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - JAX

improved glucose tolerance ( J:211773 )

♀

IMPC - JAX

nervous system

increased prepulse inhibition ( J:211773 )

♂

IMPC - JAX

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - JAX

increased bone mineral density ( J:211773 )

♂

IMPC - JAX

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - JAX