Phenotypes associated with this allele

• Allele Symbol: Msn^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5632533
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Msn^tm1b(EUCOMM)Hmgu/Msn^tm1b(EUCOMM)Hmgu	C57BL/6N-Msn^tm1b(EUCOMM)Hmgu/J	MGI:6480514
ot2	Msn^tm1b(EUCOMM)Hmgu/Y	C57BL/6N-Msn^tm1b(EUCOMM)Hmgu/J	MGI:6461450

Genotype
MGI:6480514

hm1

• Allelic Composition: Msn^{tm1b(EUCOMM)Hmgu}/Msn^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Msn^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0711_6_E04

Data Sources

IMPC Data for Msn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - JAX

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♀

IMPC - JAX

decreased hematocrit ( J:211773 )

♀

IMPC - JAX

decreased hemoglobin content ( J:211773 )

♀

IMPC - JAX

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - JAX

increased mean corpuscular volume ( J:211773 )

♀

IMPC - JAX

thrombocytopenia ( J:211773 )

♀

IMPC - JAX

decreased leukocyte cell number ( J:211773 )

♀

IMPC - JAX

immune system

decreased leukocyte cell number ( J:211773 )

♀

IMPC - JAX

Genotype
MGI:6461450

ot2

• Allelic Composition: Msn^{tm1b(EUCOMM)Hmgu}/Y
• Genetic Background: C57BL/6N-Msn^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0711_6_E04

Data Sources

IMPC Data for Msn

behavior/neurological

impaired pupillary reflex ( J:211773 )

♂

IMPC - JAX

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

decreased hematocrit ( J:211773 )

♂

IMPC - JAX

decreased hemoglobin content ( J:211773 )

♂

IMPC - JAX

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - JAX

vision/eye

impaired pupillary reflex ( J:211773 )

♂

IMPC - JAX