Phenotypes associated with this allele

• Allele Symbol: Irx1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5634290
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Irx1^tm1.1(KOMP)Vlcg/Irx1^tm1.1(KOMP)Vlcg	C57BL/6N-Irx1^tm1.1(KOMP)Vlcg/J	MGI:5767696
ht2	Irx1^tm1.1(KOMP)Vlcg/Irx1^+	C57BL/6N-Irx1^tm1.1(KOMP)Vlcg/J	MGI:6262715

Genotype
MGI:5767696

hm1

• Allelic Composition: Irx1^{tm1.1(KOMP)Vlcg}/Irx1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Irx1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 11187B-E2

Data Sources

IMPC Data for Irx1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - JAX

embryo

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal abdominal wall morphology ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6262715

ht2

• Allelic Composition: Irx1^{tm1.1(KOMP)Vlcg}/Irx1⁺
• Genetic Background: C57BL/6N-Irx1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 11187B-E2

Data Sources

IMPC Data for Irx1

behavior/neurological

decreased thigmotaxis ( J:211773 )

♂

IMPC - JAX

decreased locomotor activity ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

IMPC - JAX