Analysis Tools
behavior/neurological
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• longer time to reach the platform in a Morris water maze although other parameters of performance are normal
• in probe tests, less time is spent in the quadrant where the platform had been than is true for controls
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• open field exploratory behavior is greater than controls at day 1
• although exploratory behavior declines by day 3, it remains greater than in controls
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• poorer improvement of swim time in a forced swim test than observed in other genotypes than is seen for other genotypes
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• spend considerably less time on the open arms of an elevated maze than do controls
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• show considerable less locomotor activity than controls when housed alone for 3 days
• difference from controls disappears after being housed alone for one month
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• transient hyperlocomotion induced by methylphenidate (MPH)
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