Phenotypes associated with this allele

• Allele Symbol: Elavl1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5635064
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Elavl1^tm1b(EUCOMM)Hmgu/Elavl1^tm1b(EUCOMM)Hmgu	C57BL/6N-Elavl1^tm1b(EUCOMM)Hmgu/J	MGI:6262362
ht2	Elavl1^tm1b(EUCOMM)Hmgu/Elavl1^+	C57BL/6N-Elavl1^tm1b(EUCOMM)Hmgu/J	MGI:6262361

Genotype
MGI:6262362

hm1

• Allelic Composition: Elavl1^{tm1b(EUCOMM)Hmgu}/Elavl1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Elavl1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0594_4_E08

Data Sources

IMPC Data for Elavl1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

♀

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

♀

IMPC - JAX

limbs/digits/tail

abnormal limb morphology ( J:211773 )

♀

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

vision/eye

anophthalmia ( J:211773 )

♀

IMPC - JAX

Genotype
MGI:6262361

ht2

• Allelic Composition: Elavl1^{tm1b(EUCOMM)Hmgu}/Elavl1⁺
• Genetic Background: C57BL/6N-Elavl1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0594_4_E08

Data Sources

IMPC Data for Elavl1

behavior/neurological

impaired pupillary reflex ( J:211773 )

♂

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - JAX

vision/eye

impaired pupillary reflex ( J:211773 )

♂

IMPC - JAX