Phenotypes associated with this allele

• Allele Symbol: Ciroz^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5635119
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ciroz^tm1b(EUCOMM)Hmgu/Ciroz^tm1b(EUCOMM)Hmgu	C57BL/6N-Gm572^tm1b(EUCOMM)Hmgu/J	MGI:6262537

Genotype
MGI:6262537

hm1

• Allelic Composition: Ciroz^{tm1b(EUCOMM)Hmgu}/Ciroz^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gm572^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0741_5_G05

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

heterotaxia ( J:363359 )

abdominal situs ambiguus ( J:363359 )

bronchial situs inversus ( J:363359 )

situs ambiguus ( J:363359 )

visceral organ asymmetry ( J:363359 )

respiratory system

bronchial situs inversus ( J:363359 )

mortality/aging

embryonic lethality, incomplete penetrance ( J:363359 )

• fewer than 6% of homozygotes survive to birth