Phenotypes associated with this allele

• Allele Symbol: Iqcg^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5635126
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Iqcg^tm1b(EUCOMM)Wtsi/Iqcg^tm1b(EUCOMM)Wtsi	involves: C57BL/6N * FVB/NJ	MGI:5696801
ht2	Iqcg^esgd12d/Iqcg^tm1b(EUCOMM)Wtsi	involves: C57BL/6 * C57BL/6N * FVB/NJ	MGI:5696800

Genotype
MGI:5696801

hm1

• Allelic Composition: Iqcg^{tm1b(EUCOMM)Wtsi}/Iqcg^{tm1b(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6N * FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:218515 )

N • acrosomal cap formation is apparently normal in sperm

azoospermia ( J:218515 )

• spermatozoa lacking in the epididymus

• lack any motile sperm

abnormal spermiogenesis ( J:218515 )

• elongated spermatids lacking tails released into seminiferous tubules

• unattached sperm tails found in the lumen of seminiferous tubules

• sperm with tails are non-motile

• sperm with tails have abnormal heads

cellular

azoospermia ( J:218515 )

• spermatozoa lacking in the epididymus

• lack any motile sperm

Genotype
MGI:5696800

ht2

• Allelic Composition: Iqcg^esgd12d/Iqcg^{tm1b(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/NJ

reproductive system

reproductive system phenotype ( J:218515 )

N • acrosomal cap formation is apparently normal in sperm

azoospermia ( J:218515 )

• spermatozoa lacking in the epididymus

• lack any motile sperm

abnormal spermiogenesis ( J:218515 )

• elongated spermatids lacking tails released into seminiferous tubules

• unattached sperm tails found in the lumen of seminiferous tubules

• sperm with tails are non-motile

• sperm with tails have abnormal heads

cellular

azoospermia ( J:218515 )

• spermatozoa lacking in the epididymus

• lack any motile sperm