Phenotypes associated with this allele

• Allele Symbol: Tg(HTT*)AXwy
• Allele Name: transgene insertion A, X William Yang
• Allele ID: MGI:5635157
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(HTT*)AXwy/0	involves: FVB/NJ	MGI:5635162

Genotype
MGI:5635162

tg1

• Allelic Composition: Tg(HTT*)AXwy/0
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

dystonia ( J:219890 )

• dystonia-like head movements after 18 months of age

abnormal head movements ( J:219890 )

• abnormal and progressive chorea/dystonia-like head movements after 18 months of age

growth/size/body

weight loss ( J:219890 )

• body weight loss at 18 months of age

muscle

dystonia ( J:219890 )

• dystonia-like head movements after 18 months of age

nervous system

brain atrophy ( J:219890 )

• forebrain and cellular atrophy after 18 months of age

neuronal intranuclear inclusions ( J:219890 )

• mutant HTT aggregates in nuclear inclusions in the cortex and striatum are absent at 6 months but progressively increase between 18 and 24 months of age