Phenotypes associated with this allele

• Allele Symbol: Kif5a^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5635227
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif5a^tm1b(EUCOMM)Wtsi/Kif5a^tm1b(EUCOMM)Wtsi	C57BL/6N-Kif5a^tm1b(EUCOMM)Wtsi/J	MGI:6262754
ht2	Kif5a^tm1b(EUCOMM)Wtsi/Kif5a^+	C57BL/6N-Kif5a^tm1b(EUCOMM)Wtsi/J	MGI:6262753

Genotype
MGI:6262754

hm1

• Allelic Composition: Kif5a^{tm1b(EUCOMM)Wtsi}/Kif5a^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Kif5a^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0680_2_H02

Data Sources

IMPC Data for Kif5a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

cyanosis ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6262753

ht2

• Allelic Composition: Kif5a^{tm1b(EUCOMM)Wtsi}/Kif5a⁺
• Genetic Background: C57BL/6N-Kif5a^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0680_2_H02

Data Sources

IMPC Data for Kif5a

behavior/neurological

impaired pupillary reflex ( J:211773 )

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

vision/eye

impaired pupillary reflex ( J:211773 )

IMPC - JAX