Analysis Tools
mortality/aging
|
• although normal blastocysts are recovered in expected Mendelian ratios at E3.5, no embryos or excess resorption sites are observed at E7.5
(J:279207)
• although blastocysts appear morphologically normal at E3.5, no viable embryos are found at gastrulation stages
(J:332928)
• homozygous embryos cannot be recovered in vivo after E3.5
(J:332928)
|
embryo
|
• blastocysts fail to hatch from the zona pellucida with apparent cell death after 3 days in culture
(J:279207)
• in vitro outgrowth assays show that none of the blastocysts form a successful outgrowth after 3 days in culture, failing to hatch from the zona pellucida
(J:332928)
|
reproductive system
|
• an increased number of empty decidua is noted at E7.5
|
|
• in vitro, none of the blastocysts form a successful outgrowth after 3 days in culture
|
