Phenotypes associated with this allele

• Allele Symbol: Dst^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636893
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dst^tm1b(EUCOMM)Wtsi/Dst^tm1b(EUCOMM)Wtsi	C57BL/6N-Dst^tm1b(EUCOMM)Wtsi/Bay	MGI:5767644
ht2	Dst^tm1b(EUCOMM)Wtsi/Dst^+	C57BL/6N-Dst^tm1b(EUCOMM)Wtsi/Bay	MGI:5797492

Genotype
MGI:5767644

hm1

• Allelic Composition: Dst^{tm1b(EUCOMM)Wtsi}/Dst^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dst^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0545_3_C01

Data Sources

IMPC Data for Dst

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5797492

ht2

• Allelic Composition: Dst^{tm1b(EUCOMM)Wtsi}/Dst⁺
• Genetic Background: C57BL/6N-Dst^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0545_3_C01

Data Sources

IMPC Data for Dst

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - BCM

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM

persistence of hyaloid vascular system ( J:211773 )

IMPC - BCM