Phenotypes associated with this allele

• Allele Symbol: D6Wsu163e^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636910
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	D6Wsu163e^tm1b(EUCOMM)Wtsi/D6Wsu163e^tm1b(EUCOMM)Wtsi	C57BL/6N-D6Wsu163e^tm1b(EUCOMM)Wtsi/Wtsi	MGI:6262246

Genotype
MGI:6262246

hm1

• Allelic Composition: D6Wsu163e^{tm1b(EUCOMM)Wtsi}/D6Wsu163e^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-D6Wsu163e^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0775_2_F12

Data Sources

IMPC Data for D6Wsu163e

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased food intake ( J:211773 )

♂

IMPC - WTSI

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - WTSI

hematopoietic system

increased erythrocyte cell number ( J:211773 )

IMPC - WTSI

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - WTSI

thrombocytopenia ( J:211773 )

IMPC - WTSI

decreased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

decreased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased CD8-positive, naive alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating fructosamine level ( J:211773 )

IMPC - WTSI

decreased circulating glucose level ( J:211773 )

IMPC - WTSI

increased circulating cholesterol level ( J:211773 )

IMPC - WTSI

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - WTSI

increased circulating LDL cholesterol level ( J:211773 )

♀

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - WTSI

increased circulating serum albumin level ( J:211773 )

♀

IMPC - WTSI

increased circulating total protein level ( J:211773 )

♀

IMPC - WTSI

immune system

decreased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

decreased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased CD8-positive, naive alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - WTSI